Most of them use Henderson Hasselbalch equation with different pK values.
2.
An increase in the Tumor M2-PK values during or after therapy points towards relapse and / or metastasis.
3.
Some improvements in the methodology ( especially in the determination of the pK values for modified amino acids ) have been also proposed.
4.
He showed that proteoglycans and polysaccharides of different pK values in their end groups can be differently stained which resulted in the development of Bi-Col procedure ( Wolman, 1956 ).
5.
Calculation of the species concentrations for a polyprotic acid is more complicated unless the pK values are separated by four or more, because three or more species may co-exist at a given pH . The example of citric acid is shown at the right.